Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 188
interventional 107
Observational 70
Registry 11

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 33
Drug|placebo 20
Biological 10
Device 7
Biological|placebo 6
Other 6
Procedure 6
Dietary Supplement 5
Procedure|Radiation 2
Behavioral 1
Behavioral|Biological|Diagnostic Test 1
Behavioral|Dietary Supplement|Other 1
Behavioral|Drug 1
Biological|Dietary Supplement|placebo 1
Biological|Drug 1
Biological|Drug|Other|Procedure 1
Biological|Other 1
Device|Procedure 1
Dietary Supplement|Drug|placebo 1
Other|Procedure 1
Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 40
United Kingdom 13
France 8
China 4
Netherlands 4
Australia 3
Germany 2
Japan 2
NA 2
Spain 2
United States|Canada 2
United States|United Kingdom 2
Belgium|Bulgaria|Germany 1
Brazil 1
Canada 1
Czechia|Netherlands|Spain|Sweden 1
Denmark 1
Denmark|France|Germany|Greece|Israel|Italy|Netherlands|Russian Federation|Turkey|United Kingdom 1
Finland 1
Germany|Bulgaria|Belgium|Poland|Romania|Russian Federation|Spain 1
Hungary 1
Jordan 1
Korea, Republic of 1
Russian Federation 1
Turkey 1
United States|Argentina|Australia|Belgium|France|Germany|Mexico|Netherlands|Poland|Spain|United Kingdom 1
United States|Argentina|Austria|Belarus|Bulgaria|Canada|Chile|Colombia|Croatia|Egypt|Germany|Guatemala|Italy|Japan|Korea, Republic of|Macedonia, The Former Yugoslav Republic of|Peru|Philippines|Poland|Puerto Rico|Singapore|Thailand|Ukraine 1
United States|Australia|Brazil|Canada|Ecuador|France|Hungary|India|Israel|Latvia|Malaysia|Mexico|New Zealand|Romania|Russian Federation|Serbia|South Africa|Spain|Taiwan|Tunisia|United Kingdom 1
United States|Australia|Denmark|France|Germany|Greece|Israel|Italy|Japan|Korea, Republic of|Netherlands|Portugal|Russian Federation|Slovakia|Spain|Switzerland|Turkey|United Kingdom 1
United States|Australia|New Zealand 1
United States|Austria|Belgium|Canada|Germany|Greece|Sweden|United Kingdom 1
United States|Austria|Canada|France|Germany|Italy|Mexico|Spain|Sweden|United Kingdom 1
United States|Czechia|Hungary|Poland|Romania|Russian Federation|Serbia 1
United States|India 1
United States|Sweden|United Kingdom 1

Sites per Study

Site_count Study_Count
1 68
2 8
3 3
4 3
5 2
7 1
8 2
9 1
11 2
12 2
13 1
17 2
18 1
21 1
23 1
30 1
36 1
41 1
59 1
80 1
82 1
117 1
185 1
192 1

Phase

Phase Study_Count
N/A 29
Phase 1 29
Phase 2 15
Phase 3 12
Phase 4 9
Phase 1/Phase 2 7
Phase 2/Phase 3 4
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 28
2 42
3 9
4 6
5 4
6 2
12 1
21 1
NA 14

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 10 7.000 3.00000 1.00000 15.00000 36.0 10.0000 5.0000
1st Qu. 15 20.000 10.00000 9.50000 31.00000 51.0 45.7500 20.0000
Median 20 50.000 25.00000 30.00000 45.00000 65.5 70.0000 86.0000
Mean 20 1131.655 42.34483 34.28571 95.26667 76.5 290.9167 313.8889
3rd Qu. 25 131.000 62.00000 45.00000 138.50000 91.0 355.7500 234.0000
Max. 30 25876.000 264.00000 100.00000 354.00000 139.0 1164.0000 2000.0000

Trial Group Type

group_type Group_Count
Experimental 123
Placebo Comparator 33
Other 32
Active Comparator 31
NA 14
No Intervention 7
Sham Comparator 2

Intervention Model

intervention_model Study_Count
Parallel Assignment 49
Single Group Assignment 36
Crossover Assignment 8
Sequential Assignment 7
NA 5
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 69
Basic Science 14
Prevention 9
Diagnostic 5
NA 4
Other 3
Health Services Research 1
Screening 1
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 31
France 11
NA 5
Taiwan 4
Austria|Belgium|France|Germany|Hungary|Italy|Portugal|Spain|Switzerland 2
China 2
Germany 2
Italy 2
Korea, Republic of 2
United Kingdom 2
Canada 1
Denmark 1
France|Martinique 1
Mexico 1
Singapore 1
Spain 1
Switzerland 1

Sites per Study

Site_count Study_Count
1 56
2 6
3 5
5 1
17 1
18 1

Enrollment Metrics

Measure Observational
Min 1.00
1st Qu 60.00
Median 180.00
Mean 16545.15
3rd Qu 725.00
Max 999999.00

Observation Model

observational_model Study_Count
Cohort 42
NA 9
Case-Only 6
Case-Control 5
Other 4
Case Control 2
Defined Population 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 40
Retrospective 12
Cross-Sectional 9
NA 7
Longitudinal, Retrospective/Prospective 1
Other 1

Registries

Studies by Country

Country Study_Count
United States 5
Denmark 2
Austria 1
China 1
Germany 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 8
3 1
7 1
19 1

Enrollment Metrics

Measure Registries
Min 100.000
1st Qu 210.000
Median 320.000
Mean 5897.727
3rd Qu 921.000
Max 57053.000

Registry Model

observational_model Study_Count
Cohort 8
Case-Only 2
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 9
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
2 Years 3
5 Years 2
1 Year 1
10 Years 1
100 Years 1
16 Weeks 1
24 Years 1
3 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04452305 Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting https://ClinicalTrials.gov/show/NCT04452305 Recruiting University of Pittsburgh 2025-07-01
NCT03370627 Effect of Anti-CD303 Antibodies in Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03370627 Recruiting University Hospital, Lille 2020-01-31
NCT03345004 GAD-Alum (Diamyd) Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes https://ClinicalTrials.gov/show/NCT03345004 Active, not recruiting Diamyd Medical AB 2020-08-31
NCT03342495 Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial https://ClinicalTrials.gov/show/NCT03342495 Recruiting University of Calgary 2019-12-31
NCT03337165 Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT03337165 Completed Russian Academy of Medical Sciences 2019-05-31
NCT03280797 Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases https://ClinicalTrials.gov/show/NCT03280797 Recruiting Centre Hospitalier Universitaire de NÄ«mes 2020-11-30
NCT03266172 A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses https://ClinicalTrials.gov/show/NCT03266172 Completed GlaxoSmithKline 2018-11-21
NCT03231033 Pioglitazone Therapy of Autoimmune Pulmonary Alveolar Proteinosis Autoimmune Pulmonary Alveolar Proteinosis https://ClinicalTrials.gov/show/NCT03231033 Completed Children’s Hospital Medical Center, Cincinnati 2019-04-02
NCT03186794 Aerobic Exercise in Women With Systemic Lupus Erythematosus https://ClinicalTrials.gov/show/NCT03186794 Recruiting National Institutes of Health Clinical Center (CC) 2022-12-31
NCT03122431 Relevance of Monitoring Blood and Salivar Levels of Drugs Used in Rheumatic Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03122431 Recruiting University of Sao Paulo General Hospital 2020-06-01
NCT03044873 Effect of BMS-986165 on the Pharmacokinetics of Rosuvastatin https://ClinicalTrials.gov/show/NCT03044873 Completed Bristol-Myers Squibb 2017-03-14
NCT03006146 Evaluation of a Single Dose of Inhaled Sargramostim in Patients With Autoimmune Pulmonary Alveolar Proteinosis https://ClinicalTrials.gov/show/NCT03006146 Recruiting Children’s Hospital Medical Center, Cincinnati 2020-12-31
NCT02985190 A Study of Azacitidine in Myelodysplastic Syndrome (MDS) Associated to Systemic Auto-immune and Inflammatory Disorders https://ClinicalTrials.gov/show/NCT02985190 Active, not recruiting Groupe Francophone des Myelodysplasies 2021-07-31
NCT02972801 Testicular Tissue Cryopreservation for Fertility Preservation https://ClinicalTrials.gov/show/NCT02972801 Recruiting University of Pittsburgh 2021-01-31
NCT02925351 Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases https://ClinicalTrials.gov/show/NCT02925351 Completed Jonsson Comprehensive Cancer Center 2018-04-30
NCT02899377 A PH I Pilot Imaging Study to Evaluate Molecular Imaging Methods in HVs and pSS Pts https://ClinicalTrials.gov/show/NCT02899377 Completed GlaxoSmithKline 2018-07-12
NCT02862301 Epigenetic Evaluation of HAT/HDAC Activity in PBMC From Patients With Clinically Isolated Syndrome https://ClinicalTrials.gov/show/NCT02862301 Recruiting Centre Hospitalier Universitaire de Besancon 2020-06-30
NCT02824393 Experimental Autologous Mesenchymal Stem Cell Therapy in Treatment of Chronic Autoimmune Urticaria https://ClinicalTrials.gov/show/NCT02824393 Completed Celal Bayar University 2018-05-15
NCT02780674 A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases https://ClinicalTrials.gov/show/NCT02780674 Completed Viela Bio 2017-10-23
NCT02702180 Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis (aPAP) https://ClinicalTrials.gov/show/NCT02702180 Completed Savara Inc. 2019-04-19
NCT02682511 Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension https://ClinicalTrials.gov/show/NCT02682511 Recruiting Cumberland Pharmaceuticals 2020-12-31
NCT02647866 Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis https://ClinicalTrials.gov/show/NCT02647866 Completed Kyowa Kirin Pharmaceutical Development, Inc. 2018-09-30
NCT02644759 Transplantation of Autologous Stem Cells for the Treatment of Type 1 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02644759 Completed Stem Cells Arabia 2017-08-31
NCT02602977 the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia https://ClinicalTrials.gov/show/NCT02602977 Completed Radboud University 2016-03-31
NCT02523131 Home Testing of Day and Night Closed Loop With Pump Suspend Feature https://ClinicalTrials.gov/show/NCT02523131 Completed University of Cambridge 2018-03-31
NCT02510092 Coronary Artery and Systemic Autoimmune Disease: Diagnostics and Treatment https://ClinicalTrials.gov/show/NCT02510092 Active, not recruiting Semmelweis University Heart and Vascular Center 2020-07-31
NCT02449746 Study of Immunotherapy in Autoantibody Positive Psychosis https://ClinicalTrials.gov/show/NCT02449746 Completed University of Cambridge 2017-08-31
NCT02421276 Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome https://ClinicalTrials.gov/show/NCT02421276 Recruiting University of Colorado, Denver 2020-01-31
NCT02417155 Increasing Plasma Adrenaline Levels Through Breathing Techniques - an Explorative Study https://ClinicalTrials.gov/show/NCT02417155 Completed Radboud University 2015-07-31
NCT02293161 Single Ascending Doses Study of Anti- Interleukin-7 Receptor α Monoclonal Antibody (GSK2618960) in Healthy Volunteers https://ClinicalTrials.gov/show/NCT02293161 Completed GlaxoSmithKline 2015-09-01
NCT02280434 Phase 1 Study Accessing the Safety and Tolerability of CBP-307 https://ClinicalTrials.gov/show/NCT02280434 Completed Suzhou Connect Biopharmaceuticals, Ltd. 2015-08-31
NCT02263703 Immunogenicity of HPV Vaccine in Immunosuppressed Children https://ClinicalTrials.gov/show/NCT02263703 Completed The University of New South Wales 2016-02-29
NCT02261688 Salt and TH-17 in Healthy Human Subjects https://ClinicalTrials.gov/show/NCT02261688 Completed Brigham and Women’s Hospital 2019-07-31
NCT02129868 Automated Closed-loop in Children and Adolescents With Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02129868 Completed University of Cambridge 2015-04-30
NCT01281969 Intravenous Immunoglobulin for PANDAS https://ClinicalTrials.gov/show/NCT01281969 Completed National Institutes of Health Clinical Center (CC) 2015-12-31
NCT01993732 Ovarian Tissue Cryopreservation in Females Undergoing Procedures That Will Potentially Lead To Loss of Ovarian Function https://ClinicalTrials.gov/show/NCT01993732 Completed Medical College of Wisconsin 2018-06-28
NCT01953523 Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions https://ClinicalTrials.gov/show/NCT01953523 Completed Cell Surgical Network Inc. 2016-12-31
NCT01932476 Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes https://ClinicalTrials.gov/show/NCT01932476 Completed Joslin Diabetes Center 2014-12-31
NCT01835457 Concentration/Meditation Limits Inflammation https://ClinicalTrials.gov/show/NCT01835457 Completed Radboud University 2013-06-30
NCT01778348 Closing the Loop in Children and Adolescents With Type 1 Diabetes in the Home Setting https://ClinicalTrials.gov/show/NCT01778348 Completed University of Cambridge 2015-03-31
NCT01764594 Safety Study of CDP7657 in Patients With Systemic Lupus Erythematosus https://ClinicalTrials.gov/show/NCT01764594 Completed UCB Pharma 2014-08-31
NCT01758042 Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders https://ClinicalTrials.gov/show/NCT01758042 Recruiting Massachusetts General Hospital 2019-07-31
NCT01735123 Early Dietary Intervention and Later Signs of Beta-Cell Autoimmunity https://ClinicalTrials.gov/show/NCT01735123 Completed University of Helsinki 2016-07-31
NCT01727973 Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves’ Orbitopathy https://ClinicalTrials.gov/show/NCT01727973 Completed Sun Yat-sen University 2013-11-30
NCT01684761 Study of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple Sclerosis https://ClinicalTrials.gov/show/NCT01684761 Completed Opexa Therapeutics, Inc. 2016-10-31
NCT01656278 An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT01656278 Completed King Christian X´Hospital for Rheumatic Diseases 2017-05-31
NCT01601028 Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren’s Syndrome https://ClinicalTrials.gov/show/NCT01601028 Completed Seoul National University Hospital 2013-08-31
NCT01582880 Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis https://ClinicalTrials.gov/show/NCT01582880 Completed Massachusetts Eye and Ear Infirmary 2014-03-31
NCT01527383 A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009) https://ClinicalTrials.gov/show/NCT01527383 Completed Merck Sharp & Dohme Corp. 2013-02-26
NCT01420133 Is a Diet Necessary When Corticosteroid Treatment is Prescribed? https://ClinicalTrials.gov/show/NCT01420133 Completed Assistance Publique - Hôpitaux de Paris 2015-10-31
NCT01416350 A Single and Repeat Dose PK/PD Study to Characterise Biomarker Response in Healthy Subjects Treated With Azithromycin https://ClinicalTrials.gov/show/NCT01416350 Completed GlaxoSmithKline 2011-05-12
NCT01351805 Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain https://ClinicalTrials.gov/show/NCT01351805 Active, not recruiting Brigham and Women’s Hospital 2022-04-30
NCT04274257 A Study of the Efficacy and Safety of Rituximab in Participants With Systemic Sclerosis https://ClinicalTrials.gov/show/NCT04274257 Completed Tokyo University 2019-05-09
NCT04186871 Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren’s Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT04186871 Recruiting Bristol-Myers Squibb 2022-06-23
NCT04127747 Efficacy of Individualized Rituximab in Maintaining Remission of Moderate and Severe Systemic Lupus Erythematosus https://ClinicalTrials.gov/show/NCT04127747 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2022-12-31
NCT04041544 A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Health Subject https://ClinicalTrials.gov/show/NCT04041544 Recruiting SinoMab Pty Ltd 2020-07-31
NCT04005456 Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design https://ClinicalTrials.gov/show/NCT04005456 Recruiting Metagenics, Inc. 2020-08-31
NCT03971487 Ocrelizumab for Psychosis by Autoimmunity https://ClinicalTrials.gov/show/NCT03971487 Recruiting The Methodist Hospital System 2021-03-31
NCT03956953 Single and Multiple Dose Pharmacokinetics of BMS-986165 in a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Chinese Subjects https://ClinicalTrials.gov/show/NCT03956953 Completed Bristol-Myers Squibb 2019-09-25
NCT03907540 Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 https://ClinicalTrials.gov/show/NCT03907540 Completed Kadmon Corporation, LLC 2019-05-20
NCT03849131 Patient-Reported AutoImmunity Secondary to Cancer immunothErapy https://ClinicalTrials.gov/show/NCT03849131 Recruiting University Hospital, Strasbourg, France 2026-11-30
NCT03816345 Nivolumab in Treating Patients With Autoimmune Disorders or Advanced, Metastatic, or Unresectable Cancer https://ClinicalTrials.gov/show/NCT03816345 Recruiting National Cancer Institute (NCI) 2022-08-31
NCT03782636 Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD) https://ClinicalTrials.gov/show/NCT03782636 Recruiting University of Oxford 2022-04-14
NCT03715699 Leflunomide Treatment for IgG4-RD https://ClinicalTrials.gov/show/NCT03715699 Recruiting Peking Union Medical College Hospital 2020-12-31
NCT03656627 Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease https://ClinicalTrials.gov/show/NCT03656627 Recruiting Alliance Foundation Trials, LLC. 2022-10-31
NCT03649412 A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772 https://ClinicalTrials.gov/show/NCT03649412 Completed GlaxoSmithKline 2019-05-07
NCT03644069 A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD) https://ClinicalTrials.gov/show/NCT03644069 Active, not recruiting ImmusanT, Inc. 2019-09-30
NCT03590613 Phase I Study of GSK2982772 in Japanese Healthy Male Participants https://ClinicalTrials.gov/show/NCT03590613 Completed GlaxoSmithKline 2018-09-21
NCT03540485 Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis https://ClinicalTrials.gov/show/NCT03540485 Recruiting Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 2020-07-31
NCT03530995 Drug-drug Interaction Study Between KD025, Itraconazole, Rifampicin, Rabeprazole and Omeprazole in Healthy Volunteers https://ClinicalTrials.gov/show/NCT03530995 Completed Kadmon Corporation, LLC 2019-03-15
NCT03482752 Safety Extension Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis https://ClinicalTrials.gov/show/NCT03482752 Enrolling by invitation Savara Inc. 2021-12-31
NCT01210716 Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device https://ClinicalTrials.gov/show/NCT01210716 Completed Fenwal, Inc. 2011-05-31
NCT01205438 A Study of LY2127399 in Participants With Systemic Lupus Erythematosus https://ClinicalTrials.gov/show/NCT01205438 Completed Eli Lilly and Company 2014-08-31
NCT01196091 A Study of LY2127399 in Participants With Systemic Lupus Erythematosus https://ClinicalTrials.gov/show/NCT01196091 Completed Eli Lilly and Company 2014-07-31
NCT01093911 Safety Study of CDP7657 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus (SLE) https://ClinicalTrials.gov/show/NCT01093911 Completed UCB Pharma 2012-12-31
NCT01086631 Rituximab for Autoimmune Retinopathy https://ClinicalTrials.gov/show/NCT01086631 Completed National Institutes of Health Clinical Center (CC) NA
NCT01065285 Vaccination Against Influenza in Autoimmune Diseases https://ClinicalTrials.gov/show/NCT01065285 Completed Assistance Publique - Hôpitaux de Paris 2011-07-31
NCT01056471 Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis https://ClinicalTrials.gov/show/NCT01056471 Completed Andalusian Network for Design and Translation of Advanced Therapies 2012-06-30
NCT01055080 Insulin-free Cow Milk Formula in Prevention of Type 1 Diabetes Associated Autoimmunity - FINDIA Pilot Study https://ClinicalTrials.gov/show/NCT01055080 Completed National Institute for Health and Welfare, Finland 2006-06-30
NCT01004432 Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA) https://ClinicalTrials.gov/show/NCT01004432 Completed Janssen Biotech, Inc. 2013-07-31
NCT00977977 Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy https://ClinicalTrials.gov/show/NCT00977977 Recruiting National Institutes of Health Clinical Center (CC) 2021-01-01
NCT00975936 Phase 0 Microdose Study https://ClinicalTrials.gov/show/NCT00975936 Completed GlaxoSmithKline 2009-11-12
NCT00931489 Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD) https://ClinicalTrials.gov/show/NCT00931489 Completed University of California, Davis 2014-06-30
NCT03305419 A Safety and Pharmacokinetic (PK) Study of GSK2982772 in Healthy Subjects https://ClinicalTrials.gov/show/NCT03305419 Completed GlaxoSmithKline 2018-10-15
NCT00815282 Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease https://ClinicalTrials.gov/show/NCT00815282 Completed UMC Utrecht 2015-01-31
NCT02925299 Day and Night Closed-loop in Young People With Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02925299 Active, not recruiting Jaeb Center for Health Research 2020-06-30
NCT02219256 A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of TAK-079 in Healthy Participants https://ClinicalTrials.gov/show/NCT02219256 Completed Takeda 2016-04-30
NCT02040116 Study Evaluating Rapid Infusion Rituximab in Patients With Autoimmune Diseases https://ClinicalTrials.gov/show/NCT02040116 Completed Wake Forest University Health Sciences 2014-08-31
NCT00716066 Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases https://ClinicalTrials.gov/show/NCT00716066 Recruiting Fred Hutchinson Cancer Research Center 2026-03-31
NCT00419419 Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud’s Phenomenon https://ClinicalTrials.gov/show/NCT00419419 Completed MediQuest Therapeutics NA
NCT00820469 Study of the Influence of Plasma Exchange on the Pharmacokinetics of Rituximab https://ClinicalTrials.gov/show/NCT00820469 Completed University Hospital, Toulouse 2009-11-30
NCT00378521 Dose Response Study of a Topical Gel for the Treatment of Raynaud’s Phenomenon https://ClinicalTrials.gov/show/NCT00378521 Completed MediQuest Therapeutics NA
NCT00372177 The Use of Anti-CD4 Monoclonal Antibody (mAb)-Fragment for the Imaging of Chronic Inflammation in Patients With Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00372177 Completed Biotectid GmbH 2008-05-31
NCT00351377 Gastrointestinal and Health-related Quality of Life Outcomes in Patients With Autoimmune Diseases Treated With Mycophenolate https://ClinicalTrials.gov/show/NCT00351377 Completed Novartis 2009-06-30
NCT00304291 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) https://ClinicalTrials.gov/show/NCT00304291 Completed State University of New York at Buffalo NA
NCT00253331 Lab Study of MQX-503 in Treatment of Raynaud’s https://ClinicalTrials.gov/show/NCT00253331 Completed MediQuest Therapeutics NA
NCT00114530 Scleroderma: Cyclophosphamide or Transplantation (SCOT) https://ClinicalTrials.gov/show/NCT00114530 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2016-04-30
NCT00065390 Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome https://ClinicalTrials.gov/show/NCT00065390 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001768 Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg) https://ClinicalTrials.gov/show/NCT00001768 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001658 Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections https://ClinicalTrials.gov/show/NCT00001658 Completed National Institutes of Health Clinical Center (CC) NA
NCT00039988 Treatment of Multiple Sclerosis With Copaxone and Albuterol https://ClinicalTrials.gov/show/NCT00039988 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2006-03-31
NCT00035308 Safety and Efficacy Study of LJP 394 (Abetimus Sodium) to Treat Lupus Kidney Disease https://ClinicalTrials.gov/show/NCT00035308 Completed La Jolla Pharmaceutical Company NA
NCT00817752 Ashwagandha: Effects on Stress, Inflammation and Immune Cell Activation https://ClinicalTrials.gov/show/NCT00817752 Completed National University of Natural Medicine 2008-01-31
NCT00010387 Phase II Study of High-Dose Cyclophosphamide in Patients With Severe Autoimmune Hematologic Disease https://ClinicalTrials.gov/show/NCT00010387 Completed Office of Rare Diseases (ORD) 2007-08-31
NCT00010335 Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders https://ClinicalTrials.gov/show/NCT00010335 Completed Fred Hutchinson Cancer Research Center 2010-07-31
NCT00001630 Treatment of Autoimmune Thrombocytopenia (AITP) https://ClinicalTrials.gov/show/NCT00001630 Completed National Institutes of Health Clinical Center (CC) NA
NCT00013689 Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome https://ClinicalTrials.gov/show/NCT00013689 Completed National Institutes of Health Clinical Center (CC) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04078698 Documentation of the Safety and Effectiveness Profile of the IgG Immunoadsorbers GLOBAFFIN® and LIGASORB® and IgE Immunoadsorber IgEnio® in Clinical Routine (SEPIAR) https://ClinicalTrials.gov/show/NCT04078698 Recruiting Fresenius Medical Care Deutschland GmbH 2024-12-31
NCT03444805 EBMT ADWP Prospective Non-interventional Study: Post-AHSCT Management in SSC Patients (NISSC-2) https://ClinicalTrials.gov/show/NCT03444805 Recruiting European Group for Blood and Marrow Transplantation 2021-12-31
NCT03206099 NIAID Centralized Sequencing Protocol https://ClinicalTrials.gov/show/NCT03206099 Recruiting National Institutes of Health Clinical Center (CC) 2029-12-31
NCT03205865 Diabetes Autoimmunity Study in the Young https://ClinicalTrials.gov/show/NCT03205865 Active, not recruiting University of Colorado, Denver 2020-12-31
NCT03193177 A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03193177 Completed Tsinghua University 2018-08-31
NCT03147937 Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2) https://ClinicalTrials.gov/show/NCT03147937 Recruiting Sunnybrook Health Sciences Centre 2021-05-31
NCT03140137 Immune Checkpoint Inhibitors and Pre-existing Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03140137 Completed University Hospital, Brest 2018-01-04
NCT03114267 Involvement of Viral Infections in the Pathogenesis of Chronic Lymphocytic Thyroiditis https://ClinicalTrials.gov/show/NCT03114267 Completed Centre Hospitalier Universitaire, Amiens 2015-01-06
NCT03090425 Inflammatory/Familial Dilated Cardiomyopathy: Is There a Link to Autoimmune Diseases? TP9a https://ClinicalTrials.gov/show/NCT03090425 Completed Philipps University Marburg Medical Center 2018-12-31
NCT03018600 Continuous Glucose Monitoring on Patients With Active Autoimmune Diseases Following High-dose Predisone Treatment https://ClinicalTrials.gov/show/NCT03018600 Completed Peking Union Medical College Hospital 2016-09-30
NCT02890147 Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Case-control https://ClinicalTrials.gov/show/NCT02890147 Completed Andalusian Network for Design and Translation of Advanced Therapies 2017-10-31
NCT02890121 Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: https://ClinicalTrials.gov/show/NCT02890121 Completed Andalusian Network for Design and Translation of Advanced Therapies 2017-10-31
NCT02739386 Study of Autoimmune Disease Complications Following Ipilimumab Treatment Among Melanoma Patients With Underlying Autoimmune Diseases https://ClinicalTrials.gov/show/NCT02739386 Completed Bristol-Myers Squibb 2017-03-30
NCT02715323 Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome https://ClinicalTrials.gov/show/NCT02715323 Recruiting Singapore National Eye Centre 2020-07-31
NCT02516124 EBMT ADWP Prospective Non Interventional Study : AutoHSCT in SSc Patients https://ClinicalTrials.gov/show/NCT02516124 Completed European Group for Blood and Marrow Transplantation 2018-01-31
NCT02434458 Sudoscan in Patients With Autoimmune Disorders https://ClinicalTrials.gov/show/NCT02434458 Completed The Catholic University of Korea 2015-09-30
NCT02248545 Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients https://ClinicalTrials.gov/show/NCT02248545 Completed University of Palermo 2013-07-31
NCT01280825 The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing https://ClinicalTrials.gov/show/NCT01280825 Recruiting University of Chicago 2020-11-14
NCT01953822 Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United Kingdom https://ClinicalTrials.gov/show/NCT01953822 Completed GlaxoSmithKline 2014-08-31
NCT01917760 Pharmacokinetics Study of Gamma-aminobutyric Acid https://ClinicalTrials.gov/show/NCT01917760 Completed Huashan Hospital 2014-07-31
NCT01815996 Identify Clinical Conditions That Increase Circulating DNA Levels https://ClinicalTrials.gov/show/NCT01815996 Completed University of Florida 2016-07-28
NCT01797224 OTIS Autoimmune Diseases in Pregnancy Project https://ClinicalTrials.gov/show/NCT01797224 Recruiting University of California, San Diego 2020-01-31
NCT01773031 Pancreatic Duct Evaluation in Autoimmune Pancreatitis: MR Pancreatography https://ClinicalTrials.gov/show/NCT01773031 Completed Asan Medical Center 2015-03-31
NCT01733082 The Mycophenolate Pregnancy Registry https://ClinicalTrials.gov/show/NCT01733082 Recruiting Genentech, Inc. 2021-03-31
NCT01698515 Oral Health Assessment in Rheumatoid Arthritis and Other Autoimmune Diseases– Anti- TNF Substudy https://ClinicalTrials.gov/show/NCT01698515 Completed Johns Hopkins University 2016-06-30
NCT01611636 Clinical Characteristics of Allergy, Autoimmune and Rheumatic Diseases: A Ten Year Retrospective Study https://ClinicalTrials.gov/show/NCT01611636 Completed Far Eastern Memorial Hospital 2019-12-30
NCT04353609 Covid-19 in Patients With Chronic Inflammatory Rheumatism, Auto-immune or Auto-inflammatory Rare and Non-rare Diseases https://ClinicalTrials.gov/show/NCT04353609 Recruiting University Hospital, Lille 2020-12-31
NCT04345159 Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune Disease https://ClinicalTrials.gov/show/NCT04345159 Active, not recruiting Fondation Ophtalmologique Adolphe de Rothschild 2020-04-30
NCT04293718 Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy https://ClinicalTrials.gov/show/NCT04293718 Completed Assistance Publique - Hôpitaux de Paris 2019-07-31
NCT04119713 Autoimmunity After Checkpoint Blockade https://ClinicalTrials.gov/show/NCT04119713 Recruiting University of Pennsylvania 2023-02-24
NCT04096222 Prospective Analysis of the Th17 Cellular Response in Pemphigus Vulgaris Patients https://ClinicalTrials.gov/show/NCT04096222 Recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 2023-03-28
NCT04077840 Autoimmune Diseases and Serum Autoantibodies in NCWS and IBS Patients https://ClinicalTrials.gov/show/NCT04077840 Completed University of Palermo 2017-01-01
NCT04053374 Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis https://ClinicalTrials.gov/show/NCT04053374 Recruiting University College, London 2020-06-30
NCT04022655 Predictors of Mortality in Patients With Autoimmune Diseases Admitted to the Intensive Care Unit https://ClinicalTrials.gov/show/NCT04022655 Recruiting University of Göttingen 2019-08-31
NCT04007939 Personal Lifestyle Engine (PLX) - Personal Lifestyle Medicine Center (PLMC) https://ClinicalTrials.gov/show/NCT04007939 Recruiting Metagenics, Inc. 2020-12-31
NCT03937271 Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome https://ClinicalTrials.gov/show/NCT03937271 Active, not recruiting Taipei Veterans General Hospital, Taiwan 2019-05-31
NCT03901664 Lymphocyte Sub-populations and Auto Immune Diseases https://ClinicalTrials.gov/show/NCT03901664 Completed University Hospital, Brest 2018-04-01
NCT03848962 Collection and Distribution of Biospecimens for Novel Research Uses https://ClinicalTrials.gov/show/NCT03848962 Recruiting iSpecimen Inc 2025-12-31
NCT03843034 Endometrial Markers in Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03843034 Recruiting Odense University Hospital 2020-08-31
NCT03778840 Study of Infections in Patients With Autoimmune Diseases Treated With Rituximab https://ClinicalTrials.gov/show/NCT03778840 Recruiting University Hospital, Lille 2022-05-31
NCT03767712 Trauma as a Trigger for Autoimmunity https://ClinicalTrials.gov/show/NCT03767712 Completed University Hospital, Basel, Switzerland 2019-12-23
NCT03736278 Characteristics of Tuberculosis Infection in Rheumatic Disease https://ClinicalTrials.gov/show/NCT03736278 Completed National Taiwan University Hospital 2018-11-30
NCT03656640 Trial Assessing Safety and Efficacy of Gammanorm® in Autoimmune Diseases https://ClinicalTrials.gov/show/NCT03656640 Recruiting Octapharma 2020-11-23
NCT03562975 Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus https://ClinicalTrials.gov/show/NCT03562975 Recruiting University of South Florida 2020-08-31
NCT03531996 The Longitudinal Evaluation of Autoimmune Pulmonary Alveolar Proteinosis https://ClinicalTrials.gov/show/NCT03531996 Recruiting Children’s Hospital Medical Center, Cincinnati 2025-12-31
NCT03503747 Investigating Genetic Risk for Type 1 Diabetes https://ClinicalTrials.gov/show/NCT03503747 Recruiting University of Oxford 2021-02-28
NCT03492242 Immune CHeckpoint Inhibitors Monitoring of Adverse Drug ReAction https://ClinicalTrials.gov/show/NCT03492242 Completed Groupe Hospitalier Pitie-Salpetriere 2018-09-30
NCT01180868 The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases https://ClinicalTrials.gov/show/NCT01180868 Completed Jonsson Comprehensive Cancer Center 2011-11-30
NCT01153906 Post-marketing Safety Study of Autoimmune Diseases Following Cervarix® Vaccination https://ClinicalTrials.gov/show/NCT01153906 Completed GlaxoSmithKline 2013-09-30
NCT01086059 OTIS Autoimmune Diseases in Pregnancy Project https://ClinicalTrials.gov/show/NCT01086059 Active, not recruiting University of California, San Diego 2016-08-31
NCT00995891 Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies https://ClinicalTrials.gov/show/NCT00995891 Completed National Institutes of Health Clinical Center (CC) NA
NCT00968084 Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols https://ClinicalTrials.gov/show/NCT00968084 Completed National Institutes of Health Clinical Center (CC) NA
NCT00960713 The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders https://ClinicalTrials.gov/show/NCT00960713 Completed University Hospital, Toulouse 2012-01-31
NCT00943514 Natural History of Bronchiectasis https://ClinicalTrials.gov/show/NCT00943514 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02855840 Auto-immune Diseases and Quality of Life https://ClinicalTrials.gov/show/NCT02855840 Completed Centre Hospitalier Universitaire Dijon 2016-03-31
NCT01758250 Microvascular and Fibrosis Imaging Study https://ClinicalTrials.gov/show/NCT01758250 Recruiting Duke University 2020-12-31
NCT00737451 Association of Thyroid Autoimmunity and Chronic Urticaria https://ClinicalTrials.gov/show/NCT00737451 Completed Far Eastern Memorial Hospital 2010-11-30
NCT00692861 Autoimmunity in Neurologic Complications of Celiac Disease https://ClinicalTrials.gov/show/NCT00692861 Completed National Institutes of Health Clinical Center (CC) NA
NCT00594451 Gene-Environment Interactions in Rheumatoid Arthritis Autoimmunity Disease Severity https://ClinicalTrials.gov/show/NCT00594451 Completed University of Nebraska 2010-04-30
NCT00513591 Duke Autoimmunity in Pregnancy Registry https://ClinicalTrials.gov/show/NCT00513591 Completed Duke University 2018-11-19
NCT00485446 Thrombophilia and Thyroid Autoimmunity in Implantation Failure and Recurrent Miscarriage https://ClinicalTrials.gov/show/NCT00485446 Completed Instituto Valenciano de Infertilidad, IVI VALENCIA NA
NCT00340600 Continuation of Follow-up of DES-Exposed Cohorts https://ClinicalTrials.gov/show/NCT00340600 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT00116272 Organization of Teratology Information Services (OTIS) Autoimmune Diseases in Pregnancy Project https://ClinicalTrials.gov/show/NCT00116272 Completed Amgen 2014-06-30
NCT00001330 Study of Silicone-Associated Connective Tissue Diseases https://ClinicalTrials.gov/show/NCT00001330 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001291 Genetic and Immune Studies of Rheumatoid Arthritis and Related Conditions https://ClinicalTrials.gov/show/NCT00001291 Completed National Institutes of Health Clinical Center (CC) NA
NCT00048685 Study of Oral Bacteria in Patients With Dry Mouth https://ClinicalTrials.gov/show/NCT00048685 Completed National Institutes of Health Clinical Center (CC) NA
NCT00649246 Prospective Assessment in Newborns for Diabetes Autoimmunity https://ClinicalTrials.gov/show/NCT00649246 Completed Augusta University 2010-08-31
NCT00341198 Confirmation of Systemic Autoimmune Diseases in the Agricultural Health Study https://ClinicalTrials.gov/show/NCT00341198 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001979 Immune System Related Kidney Disease https://ClinicalTrials.gov/show/NCT00001979 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00001306 Steroid Therapy in Autoimmune Premature Ovarian Failure https://ClinicalTrials.gov/show/NCT00001306 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03276923 Maternal Autoimmune Disease Research Alliance (MADRA) Registry https://ClinicalTrials.gov/show/NCT03276923 Recruiting Duke University 2027-01-01
NCT03173144 Chronic Inflammatory Disease, Lifestyle and Treatment Response https://ClinicalTrials.gov/show/NCT03173144 Recruiting University of Southern Denmark 2019-03-31
NCT03129308 Prevalence of Cutaneous Autoimmune Phenomena in HIV Infected Patients https://ClinicalTrials.gov/show/NCT03129308 Completed Medical University of Vienna 2018-05-15
NCT02813083 Detection of Pathological Lymphocytes in Patients With Autoimmune Disease https://ClinicalTrials.gov/show/NCT02813083 Enrolling by invitation University of Minnesota 2023-09-30
NCT02775500 Apremilast Pregnancy Exposure Registry https://ClinicalTrials.gov/show/NCT02775500 Recruiting University of California, San Diego 2022-02-28
NCT02103361 Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project https://ClinicalTrials.gov/show/NCT02103361 Recruiting University of California, San Diego 2024-12-31
NCT01287689 Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study https://ClinicalTrials.gov/show/NCT01287689 Completed Technische Universität Dresden 2016-12-31
NCT03885375 Diagnostic and Imaging Indicators of Immunocardiomyopathic Patients https://ClinicalTrials.gov/show/NCT03885375 Recruiting Peking Union Medical College Hospital 2020-04-01
NCT03648918 Genetics Of Autoimmunity In Type I Diabetes https://ClinicalTrials.gov/show/NCT03648918 Recruiting Medical College of Wisconsin 2050-01-31
NCT03490539 Disease-Modifying Treatments for Myasthenia Gravis https://ClinicalTrials.gov/show/NCT03490539 Recruiting Duke University 2020-11-01
NCT03456206 Chronic Inflammatory Disease, Lifestyle and Risk of Disease https://ClinicalTrials.gov/show/NCT03456206 Active, not recruiting University of Southern Denmark 2019-07-01